NfL test predicts MS disability worsening 2 Years in Advance

NfL test predicts MS disability worsening 2 Years

According to a study published in the journal Nature Medicine, a new blood test called the Neurofilament Light (NfL) test can predict increased impairment in persons with multiple sclerosis (MS) up to two years in advance.

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The neurofilament light chain protein level in the blood is determined using the NfL test. Damage to nerve cells, as in multiple sclerosis, results in the release of neurofilament light chain into the bloodstream.

Higher blood levels of neurofilament light chain were associated with an increased risk of deteriorating impairment in the following two years in MS patients, according to the study.

The NfL test, according to the researchers, may be used to identify MS patients who are most likely to see a deterioration of their disability. People with MS could potentially use this knowledge to assist plan for the future and influence treatment decisions.

advantages of the NfL exam

For MS patients, the NfL test may offer the following advantages:

• Finding those who are most likely to have a decline in their disability: This information can then be used to advise treatment choices and assist MS patients in making long-term plans.
• Keeping an eye on the efficacy of the treatment: A new treatment is effective if there is a drop in the blood level of neurofilament light chain after it is started.
• Relapse risk prediction: An elevated blood level of neurofilament light chain indicates a potential relapse in the individual.
• Restrictions on the NfL exam

There are certain restrictions on the usage of the NfL test, and it is still in development.

The test is not limited to multiple sclerosis (MS) as neurofilament light chain can also be released into the bloodstream in the presence of other neurological disorders, including Parkinson’s and Alzheimer’s disease.
How frequently the test should be run is unclear: There are researchers who recommend doing the test every six months, while others recommend doing it annually.

In summary NfL test predicts MS disability worsening 2 Years

NfL test predicts MS disability worsening 2 Years: A promising new method for tracking MS patients is the NfL test. Through better disease management, it may enhance the quality of life for those with multiple sclerosis.